Description
Product Characteristics:
Aliases: DNAJA3 antibody, HCA57 antibody, TID1DnaJ homolog subfamily A member 3 antibody, mitochondrial antibody, DnaJ protein Tid-1 antibody, hTid-1 antibody, Hepatocellular carcinoma-associated antigen 57 antibody, Tumorous imaginal discs protein Tid56 homolog antibody
Target Information: This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]